In medicinal chemistry, employing privileged scaffolds gives researchers a jump start in searching for novel and improved therapeutic agents. The imidazole ring, which has a variety of derivatives that have shown a broad range of biological functions, is one such scaffold. New imidazole (4a-4e) derivatives were synthesized under reflux conditions or ultrasonic irradiation, and identified via melting point, FTIR, 1H NMR, 13C NMR, and mass spectroscopy. The ultrasonic-assisted reactions were compared with the reactions that proceeded under traditional heating conditions comparing the ultrasonic
This study examines the effect of academic satisfaction, student engagement and organizational commitment on academic performance and investigates the mediating role of student engagement and organizational commitment. This study used a correlational design. The research population was metalwork technology students in South-East Nigeria. The research participants were 181 mechanical technology education students and 74 mechanical technology education lecturers from universities in South-East Nigeria. Data were collected by applying a questionnaire. The hypothesis were answered with regression
Imidazole derivatives have a wide range of biological applications, including antifungal, antibacterial, antiviral, antioxidant, antiparasitic, and anticancer compounds. As a result, various imidazole derivatives have been produced and developed as potential drugs for the treatment of a variety of diseases in recent years. In this study, we describe the synthesis of new 1,2, 4, 5- tetrasubstituted imidazole’s (5a-d) with pyrazole-3-one moiety by using an ultrasonicate synthesis and compare with traditional methods, utilizing a simple synthetic process and an easy purification procedure. Ultr
The delivery of public infrastructure through the PPP scheme has been increasing in recent years. However, the problem regarding lack of funding was discovered when the project used the PPP scheme. Due to this limited funding capacity from both private and public sectors, alternative funding sources are critical to financing more infrastructure projects in the future. With the potential to reach IDR 180 trillion/year, cash waqf is seen as an innovative funding scheme for PPP projects in Indonesia. Therefore, this study aims to develop cash waqf as the funding source for the PPP scheme. An in-d
The principle of monopulse interferometer direction finding systems DF methods relies on locating the source of emission with a single received pulse. They measure the angle of arrival (AOA) of the intercepted signals using phase detectors (PD). PD measures the phase difference due to antenna spacing. In digital phase detectors, dead and blind zones caused by gate propagation delay are the most challenging factors. They cause sectors of error in phase differences measurements. In this paper, a digital phase detector using two XOR gates forming two channels has been presented. The dead and blin